Looking at life beyond illness.

Everyone deserves to live a good life. But for many that’s only possible when the medication is just right. Sometimes, the correct dose can make all the difference. By combining traditional pharmaceuticals, individualized dosing and digital health solutions – that are easy to understand and use – OnDosis is writing a new chapter in patient-centric dosing.

Benefits
Why OnDosis?

Older woman sitting at kitchen table using a dosage manager

For patients

OnDosis is developed as a drug/device combination and is ready-to-use from the get go. The Dosage Manager gives patients the precise amount of granules, pellets or mini-tablets needed to optimize treatment outcomes. OnDosis Connected Services closes the loop between patient and physician – connecting patients with services and data.

Tracking the treatment is quick and easy. Thanks to intelligent dosing, the OnDosis Dosage Manager allows for individualization and ensures the right dose at the right time to the right patient. The dose can be set or adjusted to fit a changing needs, uptitration or dose tapering scheme.

The Dosage Manager can also be protected, so only the patient can access its contents. One push at the button releases the right dose as multiparticulates such as granules, pellets or mini-tablets. This makes life easier for patients. Not only do they get the right dose, the dose is also easy to swallow.

For physicians

Today, oral solid medicines are delivered as pills or capsules in bottles or blisters. This makes dose titration and adjustments more complicated than necessary. Tablets or pills may come as 5 or 10 mg dose strengths, but what if the actual need is 7.5 mg? The Dosage Manager can individualize doses to meet these needs. And what if the need changes over time or dosing needs adoption when medicines are initiated? Standard bottles or blisters cannot monitor compliance or remind patients when they miss a dose.

With OnDosis, patients get their medicine from an intuitive and handheld device – a Dosage Manager. The dose is adjusted to each individual and the drug itself is easy to swallow – making it easier to reach the desired outcomes. For the prescribing physician, prescription is as simple as any drug/device combination. With the option of remote therapeutic monitoring and compliance tracking, the physician can get a better understanding of the effectiveness of the treatment and make decisions to improve outcome in a new way.

For payers

By optimizing dosing we improve outcomes, minimize medication waste and enable healthcare systems and governments to reduce costs and use resources more wisely by focusing on patients with the highest risks or need for interventions. Why this is important? In 2016, the annual cost for drug-related morbidity and mortality resulting from nonoptimized medication was $528.4 billion in the US alone – 16% of the country's entire healthcare expenditure*.

OnDosis solutions has the potential to improve outcomes. Thanks to the handheld and easy-to-use Dosage Manager, and in combination with services, we enable closed loop disease management. For the doctor, monitoring, follow-up and adjusting doses are quick and easy. And individualized drug titration, easily modified at the right time, improves outcomes and reduces risks of costly side effects and medication waste.

*Watanabe JH, McInnis T, Hirsch JD. Cost of prescription drug–related morbidity and mortality. Annals of Pharmacotherapy. 2018;52(9):829-837.

Current therapeutics areas

Our focus is to develop solutions in collaboration with leading pharmaceutical companies for diseases that place significant burdens on both patients and healthcare. This includes CNS related diseases such as ADHD, epilepsy, Parkinson’s, anxiety and rare diseases, cancer, immunosuppression for organ transplants and pain. Just to mention a few.

Woman and child in kitchen, the son is taking medicine using the dosage manager

ADHD

ADHD treatments needs titration of dose initially and throughout life to find the lowest effective dose. Patients often miss taking their medicine at the right time and adherence is low leading to suboptimal treatment outcomes. We want to change that.

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Immunosuppression for organ transplants

Post organ transplant, immunosuppressant medicines are given to hinder the body’s natural immunoreactions from rejecting the graft. Adjusting the dose of immunosuppressants is critical, especially during the first period after transplantation. Over the course of the lifetime, the patient need to adhere to the therapy to increase likelihood of the new organ fulfilling its function.

Immunosuppression for organ transplants

Post organ transplant, immunosuppressant medicines are given to hinder the body’s natural immunoreactions from rejecting the graft. Adjusting the dose of immunosuppressants is critical, especially during the first period after transplantation. Over the course of the lifetime, the patient need to adhere to the therapy to increase likelihood of the new organ fulfilling its function.

Rare diseases

Rare diseases impact relatively few patients, but with serious consequences. The ability to guide finding the exact right dose and tracking its effect makes OnDosis the perfect solution for several rare diseases. Dose titration and adjustments due to side effects are often seen in the label of medicines for rare diseases.

Rare diseases

Rare diseases impact relatively few patients, but with serious consequences. The ability to guide finding the exact right dose and tracking its effect makes OnDosis the perfect solution for several rare diseases. Dose titration and adjustments due to side effects are often seen in the label of medicines for rare diseases.

Pediatrics

Approximately 40 percent of children worldwide are at increased risk of adverse events such as suboptimal dosing and lack of adherence to medication regimens. We want to do something about this!

Pediatrics

Approximately 40 percent of children worldwide are at increased risk of adverse events such as suboptimal dosing and lack of adherence to medication regimens. We want to do something about this!

Our next challenge

We collaborate with our clients to create solutions for the future. Get in touch to find out what we can do for you.

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Increasing knowledge into personalized medicine has demonstrated the need for individual dosing. Drug dosage forms are urgently needed enabling individual therapy, especially for oral drug delivery.


Wening K et al. Int J Pharm. 2011 Feb 14;404(1-2):1-9.

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